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M-Nano 2025, Singapore, Nov 20-22, 2025

Dr. Mitra Mosharraf presented on Artificial Intelligence in Nano Drug Delivery: From Formulation Design to Clinical Translation. You can read her presentation abstract here : Link
Dr. Rajiv Nayar presented on Designing A Pharmaceuticallly Acceptable Drug Delivery System: Importance of Defining The Target Product Profile (TPP)

From discovery to delivery: AI’s impact on nanomedicine, a podcast on Data in Biotech by CorryBio, Nov 2025, published online Dec 31, 2025. Access the podcast: Apple, Spotify

Oral Presentation at the International Conference on Innovation in Pharma R&D
On Nov 2025, Dr. Rajiv Nayar of HTD Biosystems will present on Developing a Novel Innovative Drug Delivery System: Important Considerations.

Oral Presentation at the International Conference on Innovation in Pharma R&D
On Nov 2025, Dr. Mitra Mosharraf of HTD Biosystems will present on Artificial Intelligence in Nanomedicine: From Discovery to Clinical Development. This presentation highlights the emerging role of Artificial Intelligence (AI) and Machine Learning (ML) in accelerating nanomedicine development. Applications across the R&D, from discovery and formulation design to CMC development and clinical trial optimization are explored. Emphasis is placed on how AI/ML approaches can improve predictive modeling, enable data-driven decision-making, and reduce development timelines.

Oral Presentations at the 2025 AAPS PharmSci 360 conference, San Antonio.
HTD's CSO Dr. Mitra Mosharraf delivered a hot topic symposium talk on "Strategies for manufacturing and analysis of lipid-based therapeutics and vaccines" on NOV 10th. She also chaired a session on the role of AI/ML in accelerating development of nanomedicines on Nov 12th, where she delivered a talk on the limiations of AI/ML, regulatory requirements and future perspective.

Strategies for manufacturing and analysis of lipid-based therapeutics and vaccines.
The role of AI/ML in accelerating development of nanomedicines

A few pictures from Dr. Mosharraf's presentations at the 2025 AAPS PharmSci360 shows great interest on the topics.

Join our Booth 307 at the AAPS NBC in Boston in May 2025 and let's discuss formulation and delivery of biologics, high concentration protein formulation development and lyophilization.
Also don't miss Dr. Mosharraf's rapid fire talk on how we use DOE to accelerate formulation development.

Oral Presentation at the AAPS National Biotechnology Conference (NBC), Boston, MA, May 2025.
Dr. Mitra Mosharraf will give a rapid fire presenttaion on Design of Experiments to Accelerate Formulation Development of Complex Modalities. This talk will explore the application of DoE in accelerating formulation development for complex biologics. Key topics will include experimental design strategies, selection of independent variables, and response surface methodologies to enhance stability, efficacy, and manufacturability. Case studies will highlight how DoE enables rapid iteration, robust data generation, and predictive modeling to streamline development timelines and reduce formulation risk.

FlowCam Imaging and Analytical Services for Sub-Visible Particles

At HTD Biosystems, we use FlowCam Imaging to measure sub-visible particles in parenteral products. At HTD Biosystems, we use FlowCam to characterize subvisible particles using the minimum amount of sample (100 µL) during formulation development. We can also use it for protein developability screening and determination of protein aggregation during formulation and process developments, aseptic fill-finish, and release of GLP lots.
We’re happy that FlowCam can quantify particulate matter and help us identify which types of particles we have as an orthogonal technique to other methodologies. FlowCam provides images of the particles but also accounts for the number of particles in a range we could not previously analyze with our in-house instrumentation. FlowCam has been a versatile tool for us in all the different projects or stages of development including protein screening, formulation development and stability studies.

Nanoparticle Characterization

We’re proud to announce that Dr. Mitra Mosharraf, Chief Scientific Officer at HTD Biosystems, was selected as one of the featured experts in the "Ask the Experts" session on Nanoparticle Characterization, organized by AAPS on January 27, 2025. This session brought together leading scientists to discuss cutting-edge techniques and best practices in the characterization of nanoparticles, critical for advancing nanomedicine and biologics.
Dr. Mosharraf shared insights drawn from over 24 years of experience in biologics and nanomedicine development, focusing on innovative strategies for ensuring the stability, efficacy, and quality of nanoparticle-based formulations.

At HTD Biosystems, we specialize in nanoparticle characterization and formulation development, offering comprehensive services for liposomes, lipid nanoparticles (LNPs), antibody-drug conjugates (ADCs), and other complex modalities. Our expertise in Design of Experiments (DoE) and advanced analytical techniques ensures robust, reproducible results, accelerating your drug development process from bench to clinic.
Ready to optimize your nanoparticle formulations?
Contact us today to learn how our expert team can support your next breakthrough.

October 7th, 2024

Participation at the AAPS PharmSci 360, Oct 20-23, Salt Lake City

Don't miss out HTD's presentations at PharmSci 360. This year HTD's president Dr. Rajiv Nayar will deliver a prologue talk on LNPs and will be the moderator for "Phase Appropriate Strategies for Gene and Cell Therapy Regulatory Compliance" session.
Our Chief Scientific Officer, Dr. Mitra Mosharraf, will present two scientific posters in Salt lake City and will start her term as the Chairman of the Nanotechnology Community for 2025. Please come by our posters and let's talk about LNP stability, Protein formulation, and Lyophilization.
We will also be attending a Mentoring Breakfast on Tuesday morning.
Mentoring Breakfast:
Tuesday 7 - 8:30 am, Salt Lake AB, Hyatt Regency Hotel
Prologue talk:
LNP's: Formulations that Pushed Back COVID-19. Speaker: Dr. Rajiv Nayar
Moderator:
Dr. Rajiv Nayar will be the moderator for "Phase Appropriate Strategies for Gene and Cell Therapy Regulatory Compliance" session.
Tuesday, 9-10 am
New Chair of the Nanotechnology Community: Dr. Mitra Mosharraf
Monday 5 -6 pm, 150 DEFG
Posters:
Characterization of Protein Antigens in Liposomal Vaccines Using Differential Scanning Fluorimetry. Presenter: Dr. Mitra Mosharraf
Monday, 2:30 pm, M1430-11-60

Predicting the Aggregation Behavior of Liposomes Using Thermal Analysis. Presenter: Dr. Mitra Mosharraf
Wednesday, 10:30 am, W1030-3-16


May 14, 2024

Exhibition & Presentations at the AAPS National Biotechnology Conference, San Francisco, CA

AAPS NBC was a great conference with a busy tradeshow, excellant program and good science. With a tradeshow, two scientific posters and a prologue talk, and lots of networking we maximized our presence at the NBC. Thank you to all who stopped by our booth and came by our posters.

Prologue talk: Opportunities and Challenges for Lipid-Based Drug Delivery Systems for Biopharmaceuticals. Speaker: Dr. Rajiv Nayar
Poster 1: Predicting the Aggregation Behavior of Liposomes Using Thermal Analysis. Presenter: Dr. Mitra Mosharraf
Poster 2: Characterization of Protein Antigens in Liposomal Vaccines Using Differential Scanning Fluorimetry. Presenter: Dr. rajiv Nayar.

Oct 26, 2023

Exhibition & Presentations at the AAPS PharmSci 360 in Orlando, FL

This year we had a wonderful tradeshow at the AAPS PharmSci 360. During this conference also HTD's president Dr. Rajiv Nayar presented a scientific poster on our COVID-19 vaccine collaboration at the AAPS PharmSci 360 in Orlando, FL. Other co-authors were Dr. Mitra Mosharraf and Dr. Aryo Sorayya.
Poster: A Versatile Room Temperature Stable Lipid Nanoparticle COVID-19 Protein-Based Vaccine.

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HTD is a private company located in Livermore, California. HTD has worked and collaborated with other companies, governments, and academia. Our researchers have helped other companies develop their products.

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