Liposomal Drug Delivery Systems

Specializes in the development of systems for delivering drugs to specific parts of the body in order to increase their effectiveness and minimize side effects.

At HTD, we have long-standing expertise in the development of targeted drug delivery and liposomal systems.

These systems are designed to deliver therapeutic agents specifically to the site of action, with the aim of improving the effectiveness and safety of the treatment.  Packaging toxic anticancer drugs into liposomal systems also reduces the toxicity associated with the free drug and increased payload delivery to the tumor site.

We have a dedicated team of scientists and engineers who are experts in the design, synthesis, and optimization of targeted drug delivery systems. We use a variety of approaches, including nanoparticles, liposomes, and other nanocarriers, to enable the targeted delivery of small molecule drugs, biologics, and nucleic acid therapies.

Our targeted drug delivery systems are designed to overcome the challenges of traditional drug delivery, such as poor bioavailability, low stability, and off-target toxicity. We have a strong track record of success in the development of targeted drug delivery systems for a range of indications, including cancer, inflammation, and infectious diseases.

We are committed to advancing the field of targeted drug delivery and to developing innovative solutions that improve the effectiveness and safety of treatments for patients.​​​​​​​

What is targeted drug delivery?

A drug delivery system is a method or device used to deliver a therapeutic agent to the site of action in the body. The goal of a drug delivery system is to enhance the effectiveness and safety of the treatment by improving the pharmacokinetics (i.e., the way the drug is absorbed, distributed, metabolized, and eliminated) and pharmacodynamics (i.e., the biological effects of the drug) of the drug.

There are many different types of drug delivery systems, including oral, parenteral (e.g., injectable), topical, inhalation, and implantable. Each type of drug delivery system has its own advantages and limitations, and the most appropriate delivery system depends on the properties of the drug and the desired therapeutic effect.
Some examples of drug delivery systems include:
  • Injections: These are parenteral formulations that are administered by injection, either intravenous (IV), intramuscular (IM), or subcutaneous (SC).
  • Patches: These are topical formulations that are applied to the skin and deliver the drug through the skin and into the bloodstream.
  • Inhalers: These are formulations that are inhaled through the mouth or nose and delivered to the lungs.
  • Implants: These are drug delivery systems that are implanted in the body, either subcutaneously or in a specific organ, and release the drug slowly over a prolonged period of time.
Overall, drug delivery systems play a crucial role in the effectiveness and safety of therapeutic agents, and their development is a key area of research and innovation in the pharmaceutical industry.

Liposomal Drug Delivery

Liposomes are small, spherical vesicles that are composed of phospholipid bilayers and are commonly used in drug delivery applications. Liposomes can be used to deliver a wide range of drugs, including small molecules, proteins, and nucleic acids, and they offer several advantages over traditional drug delivery systems, including:
  • Targeted delivery: Liposomes can be designed to target specific cells or tissues in the body, which can improve the efficacy and specificity of the drug delivery.
  • Increased stability: Liposomes can protect the drug from degradation and improve its stability during storage and administration.
  • Enhanced bioavailability: Liposomes can improve the bioavailability of drugs by increasing their solubility and penetration through cell membranes.
  • Reduced toxicity: Liposomes can reduce the toxicity of drugs by limiting their exposure to non-targeted cells and tissues.
Liposomal drug delivery is a promising approach for the delivery of a wide range of drugs, and HTD has expertise in the development of liposomes for drug delivery applications. Our team of scientists is skilled in the design and optimization of liposomes for specific drugs and indications, and we are dedicated to supporting the development of safe and effective liposomal drug delivery systems.