Rational Design & Accelerated Formulation of Biologics
Formulation Development
Formulation development is an important aspect of product development. We utilize our extensive experience, expertise, and novel technologies to address complex formulation and drug delivery problems.
At HTD we offer several analytical services. The approach we use for formulation is to identify the most stable conformation of the protein using a number of biophysical approaches. Characterizing and stabilizing the conformation of a molecule is key to developing a successful, stable, and robust formulation.
Design of Experiments or DOE is a powerful tool that assists formulation scientists with high throughput drug formulation development. The main purpose of using DOE is to minimize the number of trials and maximize the results.
We provide customized lyophilization services and develop efficient freeze-drying cycles for various biotech drugs ranging from small molecules, peptides, proteins, and drug delivery systems (e.g liposomes).
HTD is a private company located in Livermore, California. HTD has worked and collaborated with other companies, governments, and academia. Our researchers have helped other companies develop their products.
